The weekend is packed with Pacquiao vs. Barrios and Usyk vs. Dubois on the card. Here are picks for the biggest fights.

Manny Pacquiao pushed back against his doubters, the odds and even Father Time on Saturday night — and nearly made some history.

Mario Barrios is a -280 favorite to defeat Manny Pacquiao according to the odds at FanDuel Sportsbook. A bet on the underdog Pacquiao would pay out at +210. These odds suggest that Barrios has a 73.7% chance of winning the fight. When you consider the age and reach advantage he possesses, the betting odds seem about right.