The Guardians’ leading hitters are Jose Ramirez at 142 wRC+, Steven Kwan at 109 wRC+ (expected back today), and Kyle Manzardo at 100 wRC+. The Orioles’ leading hitters are Ryan O’Hearn at 135 wRC+, Ramon Laureano 134 wRC+, Gunnar Henderson 124 wRC+, Jordan Westburg 118 wRC+ and Colton Cowser at 106 wRC+.

Pregame analysis and predictions of the Baltimore Orioles vs. Cleveland Guardians MLB game to be played on July 21, 2025 on ESPN.

Since then, though, Cleveland has been red hot. They’ve won eight of their last 10 games, including a sweep of the Astros and series wins over the White Sox and Athletics, the two worst teams in the American League. Now they’ll get to face the third-worst team, the Orioles, with a chance to keep the good times rolling.

The Cleveland Guardians defeat the Baltimore Orioles 6-3, marking their fourth win in five games since the All-Star break.