Acute decompensated heart failure (ADHF) is responsible for more than 1 million hospital admissions each year in the US. Clinicians and scientists have developed therapeutic strategies that reduce ...

Addrenex Pharmaceuticals Inc., founded 18 months ago to develop a sustained-release formulation of clonidine, recently complemented that program with additional compounds aimed at the adrenergic ...

Researchers discover a new way to keep the heart pumping, which could lead to new drugs for heart disease. The research offers the possibility of developing a new, and potentially more effective, ...

The use of β blockers in congestive heart failure presents a therapeutic challenge for patients with acute episodes of decompensation. Such patients may be less responsive to positive inotropic agents ...

Experiments with pepducins, peptides derived from receptor molecules, may lead to a new class of drugs for heart disease. Certain pepducins, report scientists based at Thomas Jefferson University, are ...

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The Nature Communications study found ...

News-Medical spoke to researchers Dr. Nirmal Robinson, Dr. Vincenzo Desiderio, and Dr. Antonio Barbieri about their latest research into beta-blockers, and how they could potentially be used to treat ...

BUFFALO, N.Y. -- In their continuing search for promising targets for treating mental disorders, a group of neuroscientists at the University at Buffalo has identified a pathway critical to the ...

Mouse neurons stained for enzyme PDE4D5 (green). New work from UC Davis shows that this enzyme plays a key role in memory formation. The process by which memories are formed in the hippocampus region ...

(PHILADELPHIA) -- About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention (CDC). Two ...