Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

Many people notice that certain foods become harder to tolerate with age. One possible reason is damage to the intestinal epithelium, a thin, single ...

Chinese Medical Journals Publishing House Co., Ltd. The small intestine is not only essential for digestion and nutrient absorption but also for immune regulation and maintaining a balanced microbial ...

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

Nope, this isn’t a small, prickly mammal with a flashy dye job, but a single intestinal epithelial cell. The colorful, hairlike structures are microvilli, which are designed to maximize the cell’s ...