Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...
Engineered dendritic cells capture tumor EVs, enhancing antigen presentation and T cell activation to boost cancer immunotherapy in preclinical models.
Among adults with evidence of systemic mast cell activation, bone marrow samples allowed for detection of 13 additional ...
Cells in the immune system don't always fight; they often rest and wait for threats, like viruses or bacteria. When such threats emerge, the cells activate to defend the body. This delicate balance ...
Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...
Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...
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Sugars found in the ocean can trigger cancer cells to self-destruct, reshaping treatment
Cancer treatment often sounds distant and technical, so stories about it can feel hard to enter. Yet, everyday curiosity ...
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