While the buildup of sticky proteins called amyloid plaques in the brain has been repeatedly linked to Alzheimer's disease, the role of blood in the formation of the condition has been less clear.

A 70-year-old man undergoing a leg amputation was diagnosed with a rare combination of acquired hemophilia A and Factor XII ...

Please provide your email address to receive an email when new articles are posted on . In this video, Iberia Romina Sosa, MD, PhD, discusses the results of a study presented at ASH Annual Meeting and ...

Inhibition of coagulation factor XII (FXII) activity after traumatic brain injury (TBI) could minimize secondary brain damage without the risk of inducing bleeding, according to a new mouse study.

Polyphosphate is an inorganic procoagulant polymer. Here we develop specific inhibitors of polyphosphate and show that this strategy confers thromboprotection in a factor XII-dependent manner.

ANDEMBRY® is a first-in-class monoclonal antibody treatment that inhibits activated Factor XII (FXIIa), the initiating factor in the HAE pathway, and offers the first pre-filled pen presentation ...

Factor deficiency or inhibition. The possible causes of the isolated prolonged aPTT in this case include factor deficiencies and factor inhibitors. Prolongation of both the PT and aPTT suggests ...

Coen Maas, Joost C. M. Meijers, J. Arnoud Marquart, Kamran Bakhtiari, Cees Weeterings, Philip G. de Groot, Rolf T. Urbanus, Earl W. Davie Proceedings of the National ...

Hereditary angioedema (HAE) is a rare condition that causes fluid to build up throughout your body, triggering sudden and repeated serious swelling. This is the most common type and happens because of ...

Experimental data indicate that reducing factor XI levels attenuates thrombosis without causing bleeding, but the role of factor XI in the prevention of postoperative venous thrombosis in humans is ...