Mice with a functional human immune system serve as an invaluable tool to study the development and function of the human immune system in vivo. A major technological limitation of all current ...

Humanized immune system (HIS) mouse models have become indispensable for advancing translational research in immuno-oncology, autoimmune disorders, and infectious disease. This webinar will begin with ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

Desmoplastic nodular medulloblastoma: A National Cancer Database analysis of patient demographics and survival. A phase 1 study to evaluate the safety and tolerability of BXQ-350, a novel sphingolipid ...

Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...

In a recent publication, researchers from Colorado State University presented the development and evaluation of humanized mice as a hybrid dual-use model for testing therapeutics against both HIV and ...

Tolerance Bio, a biopharmaceutical company pioneering innovative approaches to extending healthspan by preserving, restoring, ...

Researchers corrected lamin A gene mutations, preventing skeletal and cardiac abnormalities and extending mice lifespans.

Cutting-edge machine learning tools reveal hidden patterns in Alzheimer’s disease mouse behavior, opening the door to innovative treatments targeting neuroinflammation. Study: Machine learning reveals ...