The yeast DEL assay is an effective method for measuring intrachromosomal recombination events resulting in DNA deletions that when occurring in mammalian cells are often associated with genomic ...
High doses of X-rays and other kinds of ionizing radiation can damage the DNA present in the cell nucleus, a phenomenon which can both lead to the development of cancer in humans and be used to kill ...
Recent release of the waste water from Japan's Fukushima nuclear disaster stirred apprehension regarding the health implications of radiation exposure. Classified as a Group 1 carcinogen, ionizing ...
This is a preview. Log in through your library . Abstract Clustered DNA damage is considered an important factor in determining the biological consequences of ionizing radiation. In this study, we ...
We have generated transgenic mice carrying targeted deletions of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene. These animals offer the unique opportunity to gain insights into ...