WRAL

Eyes are the prize: Identifying the cause of lens luxation in terriers

Certain breeds of dog are highly susceptible to a form of inherited eye disease known as primary lens luxation. Lens luxation occurs when problems with the structures that support the lens in the eye ...
Yahoo Finance

Synlogic Announces Publication of Preclinical and Clinical Data for SYNB1353 as a Potential Treatment for Classical Homocystinuria

CAMBRIDGE, Mass., Feb. 02, 2024 (GLOBE NEWSWIRE) -- Synlogic, Inc. (Nasdaq: SYBX), a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases, announced today ...
Nasdaq

Aeglea BioTherapeutics Receives FDA Rare Pediatric Disease Designation for ACN00177 for the Treatment of Homocystinuria

AUSTIN, Texas, Dec. 1, 2020 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ: AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative ...
Nature

Characterisation of Five Missense Mutations in the Cystathionine Beta-Synthase Gene from Three Patients with B

Direct-sequence analysis of PCR-amplified CBS cDNA was employed to identify sequence mutations in the CBS gene from 3 patients with pyridoxine-nonresponsive homocystinuria. These mutations are ...
Nature

Identification and functional analysis of cystathionine beta-synthase gene mutations in patients with homocystinuria

Homocystinuria is the most common inborn error of sulfur amino acid metabolism. It is most commonly caused by cystathionine beta-synthase (CBS) deficiency, which is ...