The TP53 gene is mutated in around 50% of cancer cells, but in addition to its role in tumor suppression, cancer cells ...

Because only part of the man's sperm carried the mutation, only the second round of genetic testing revealed the problem. By then, it was already too late.

A genetic mutation that carries a 90% cancer risk has been passed on by an unwitting sperm donor to dozens of children, a ...

TP53 mutations are crucial in cancer development and treatment response, influenced by genetic and environmental factors. In CLL and AML, TP53 serves as a significant prognostic marker, affecting ...

A sprawling international fertility scandal is forcing regulators and doctors across Europe to rethink donor screening after ...

European fertility clinics used cancer-causing sperm for 17 years, prompting urgent calls for genetic screening reforms and international donor limits.

The TP53 gene is one of the most important tumor suppressor genes in the human body. It plays a key role in controlling cell ...

Some children have already died and only a minority who inherit the mutation will escape cancer in their lifetimes.

Nearly 200 children across Europe were conceived using sperm carrying a dangerous cancer-linked gene mutation. The case raises urgent questions about donor screening and international fertility ...

A SPERM donor who unknowingly carried a cancer-causing gene has fathered at least 197 children across Europe, some of whom have already died. Only a small number of those who inherit the mutation ...

A Danish sperm donor unknowingly carried a rare TP53 gene mutation, leading to nearly 200 children conceived across 14 countries potentially facing increased cancer risk. Standard screening failed to ...

Carrick Therapeutics Inc., an oncology-focused biopharmaceutical company discovering and developing highly differentiated therapies, today announced positive results from the Phase 2 SUMIT-BC clinical ...