Mesenchymal stem cells (MSCs) are multipotent progenitors that hold considerable promise for regenerative medicine, particularly in the reconstruction and repair of bone. Their inherent capacity to ...

Thyroid development represents a complex orchestration of cellular migration, differentiation and folliculogenesis, all of which are tightly regulated by an interplay of signalling pathways and ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...

The cell and gene therapy industry has achieved breakthroughs once thought impossible, translating novel concepts into real therapeutic options for patients. The FDA has now approved 43 cell and gene ...

Cell biology is a branch of biological sciences that investigates the structure, function, dynamics, and regulation of cells as the fundamental units of life. It encompasses the study of cellular ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...