Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...

The Single-antigen Bead (SAB) assay has revolutionized the detection of anti-HLA antibodies, which are critical in transplantation medicine. Despite its advantages, several limitations and challenges ...

When a patient undergoes an organ transplant, failure to match the donor and recipient can lead to the recipient's immune system attacking the new organ, a process triggered by a specific HLA (human ...

No signs of graft rejection or de novo donor-specific HLA antibodies - Tegoprubart continues to demonstrate a favorable safety and tolerability profile IRVINE, Calif, March 16, 2026 (GLOBE NEWSWIRE) - ...

Despite advances in the field of organ transplantation, industry challenges such as a shortage of viable organs for transplantation remain. It’s an unfortunate truth: the number of patients who need ...

Immunotherapies have revolutionized the way we treat cancer by amping up a person’s own immune system to help fight this disease. Dr. Josh Hill, a physician-scientist in the Vaccine and Infectious ...

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically ...

Patients with celiac disease have gluten-specific CD4+ T cells that recognize gluten via disease-associated human leukocyte antigen (HLA) molecules, specifically HLA-DQ2.5, leading to immune ...

BEIJING & SHANGHAI--(BUSINESS WIRE)--Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (“Biocytogen”, HKEX: 02315) and CtM Biotech (Shanghai) Co., Ltd ("CtM Bio") today jointly announce that the ...

Expert Rev Clin Immunol. 2008;4(3):391-399. New, solid-phase technologies for HLA antibody screening and identification have emerged that are more sensitive and more specific than previous testing ...