Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells. However, most genetic disorders are caused by dozens or even thousands of ...

Aging may "erase" the epigenetic markers that control gene expression in the brain, and this may snowball to cause unintended ...

Why are some people unable to hear from birth, even though their inner ear appears intact? One possible cause lies in the ...

Recent research indicates a link between an animal’s gut bacteria and brain function. This may be true in humans, too.

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment and ...

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient’s cells. However, most genetic disorders are caused by dozens or even thousands of ...

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of ...

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have ...

The powerful gene-editing technique CRISPR–Cas9 might offer a way to make safer, more effective cancer-fighting immune cells ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.