Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

Brains with chronic traumatic encephalopathy (CTE) show DNA damage similar to Alzheimer’s. Study links genetic stress to ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

For the first time, researchers have filmed in real time the disassembly of DNA at the atomic scale. This strand separation is the first step in DNA replication. This breakthrough, published in Nature ...

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

Using an atomic force microscope tip as a pen and different single-stranded DNA as inks, scientists at Northwestern University have demonstrated a technique that could lead to the ultimate ...

CHAMPAIGN, Ill. — Researchers report that a single-stranded DNA-binding protein (SSB), once thought to be a static player among the many molecules that interact with DNA, actually moves back and forth ...

As cells divide, they must copy all of their chromosomes once and only once, or chaos would ensue. How do they do it? By Amber Dance/Knowable Magazine Published Jul 7, 2023 6:00 PM EDT This article ...

Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.