Leucine-rich repeat–containing protein 15 (LRRC15) is a cell surface protein that has emerged as a significant biomarker in cancer biology. This protein is minimally expressed in normal healthy tissue ...

Dr. Bernd Pichler is a distinguished pioneer in preclinical and translational imaging, renowned for his groundbreaking work ...

RECIST was developed in 2000 by the National Cancer Institute, European Organization for Research and Treatment of Cancer, and National Cancer Institute of Canada, with revision to RECIST 1.1 in 2009 ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

Protein tyrosine kinase-7 (PTK7), a member of receptor tyrosine kinase superfamily initially identified as colon carcinoma kinase-4, is highly expressed in various human malignancies. Its expression ...

Journal of Nuclear Medicine October 2025, jnumed.125.270151; DOI: https://doi.org/10.2967/jnumed.125.270151 ...

Journal of Nuclear Medicine October 2025, jnumed.125.270215; DOI: https://doi.org/10.2967/jnumed.125.270215 ...

Targeted diagnosis and therapy enable precise tumor detection and treatment. Successful examples for precise tumor targeting are diagnostic and therapeutic radioligands. However, patients with tumors ...

Quantitative PET imaging relies on accurate attenuation correction. Recently, there has been growing interest in combining state-of-the-art PET systems with MR imaging in a sequential or fully ...

Cerenkov luminescence imaging (CLI) provides a convenient approach to image the in vivo distribution of radiopharmaceuticals using optical instruments. It has attracted much attention and been widely ...

The impact of PET image acquisition and reconstruction parameters on SUV measurements or radiomic feature values is widely documented. This scanner effect is detrimental to the design and validation ...

Hybrid PET/MR systems have rapidly progressed from the prototype stage to systems that are increasingly being used in the clinics. This review provides an overview of developments in hybrid PET/MR ...